Marvel Comics

Daniel Way's Deadpool run launched in 2008 and defined the character for a generation of readers who came to Marvel through the film era — it's the run that pushed the fourth-wall breaking and comedic irreverence to their most extreme expression, making Deadpool one of Marvel's best-selling characters in the process. Way's first volume drops the mercenary into the Secret Invasion event and then into a sustained antagonistic relationship with Norman Osborn's Dark Reign, finding endless comedy in Deadpool's attempts to be taken seriously as a professional assassin.